ISRAEL 
HIGH-TECH & INVESTMENT REPORT

from the July 2003 issue


Medtronic and MindGuard to Collaborate on Therapy for High-Risk Stroke Patients

Medtronic, Inc. (NYSE:MDT) announced that it has completed an equity investment in MindGuard Ltd., a privately held developer of devices for high-risk stroke patients. As part of the agreement, Medtronic will secure European distribution rights for MindGuard's Divertersystem. The size of the investment was not disclosed. MindGuard, based in Caesarea, Israel, has developed The Diverter System, an implantable system intended to be deployed in the carotid arterial bifurcation - the main bifurcation point for blood flow to the brain from the heart. There it serves to divert cardioemboli (plaque-like debris) in the arterial system away from the brain. Without this potential diversion therapy, cardioemboli can flow to the brain, creating blockages that may lead to ischemic stroke. "We are pleased to initiate this relationship with MindGuard in order to help bring to market this technology for potential stroke victims," said Bill Hawkins, president of Medtronic Vascular. "The Diverter System offers a minimally-invasive and preventative therapy option to physicians treating high-risk stroke patients. This agreement serves to further expand Medtronic Vascular's expertise intothe area of stroke prevention."

MindGuard Ltd. is an Israeli company, founded in 2000 focused on developing and marketing a portfolio of unique catheter and implant technologies to treat and prevent stroke, and other cardiovascular and cerebrovascular diseases.

Medtronic, Inc., headquartered in Minneapolis, is the world's leading medical technology company, providing lifelong solutions for people with chronic disease.



Reprinted from the Israel High-Tech & Investment Report July 2003

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