ISRAEL 
HIGH-TECH & INVESTMENT REPORT

from the June 2003 issue


Boston Scientific Signs Agreement for Advanced Imaging and Navigation Technology

Boston Scientific Corporation (NYSE: BSX ) the world's largest medical device company dedicated to less invasive therapies announced that it has signed an agreement with MediGuide, Inc., a private company with development offices in Haifa, Israel.

The agreement includes an equity investment in MediGuide by Boston Scientific, co-development responsibilities for integrating Boston Scientific's device platforms with MediGuide's proprietary guidance system, exclusive global distribution and an option for Boston Scientific to acquire MediGuide at a future time.

Elbit Systems Ltd. (Nasdaq:ELST) is a majority shareholder in MediGuide. Other investors in MediGuide Inc. currently include VitaLife, V.C., The Fishman Group, Docor International and D.O.H. Investment Ltd. The agreement calls for developing and commercializing of technology platforms in the field of 3-D intravascular imaging and intrabody navigation. The initial focus of the alliance will be on interventional cardiology.

MediGuide has developed an advanced navigation system known as the Medical Positioning System (referred to as MPS), which enables the real time tracking of miniature sensors integrated into therapeutic and diagnostic medical devices. These "MPS ready" devices will allow physicians to accurately track progression of the device as they are manipulated through the human anatomy while continuously registering their exact location and orientation utilizing advanced diagnostic systems such as Boston Scientific's intravascular ultrasound (known as IVUS) system as well as additional non-invasive diagnostic systems including angiography, magnetic resonance imaging (MRI) and computed tomography scanning (CT).

MPS is designed to monitor the exact location and orientation of a miniature sensor that can be integrated into existing catheter-based therapeutic and diagnostic devices. This technology would more accurately track the location of the device as it is manipulated through the body and delivered to the treatment site.

In addition to opportunities in cardiovascular interventions, the alliance will explore opportunities to develop "MPS-ready" devices in the fields of radiology, neurosurgery, oncology, endoscopy, orthopedics and other medical specialties.

Boston Scientific and MediGuide initially plan to develop a next generation intravascular ultrasound (IVUS) system that would provide physicians a three-dimensional intravascular image of coronary arteries by integrating Boston Scientific's IVUS system and MediGuide's Medical Positioning System (MPS). This enhanced imaging capability would help physicians better assess the condition of the artery and treatment options.



Reprinted from the Israel High-Tech & Investment Report June 2003

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