ISRAEL 
HIGH-TECH & INVESTMENT REPORT

from the March 2003 issue


New Trends in Investments

Medical Devices Companies Move to the Forefront New Directions are detected as Medical Devices and Biotechnology Companies emerge as a new focus of investment attention.

Background
Israel continues to have the highest number of physicians per capita in the world. They are providers of a high level of medical services to a population which has been become pampered by the availability of excellent medical care in terms of the quality of the medical profession along with a well developed infrastructure of hospitals and private and public clinics. The hospitals and clinics have the benefit of substantial support from the Ministry of Health. The countrys legislators are well aware of the populations penchant for a high quality of medical care and do not hesitate to allocate increases in the annual budget for health care. From time to time, we report on medical research in the countrys medical schools and and hospitals. The high level of expertise accumulated there was rewarded as the US Food and Drugs Administration, nearly a decade ago designated Israeli hospitals as suitable for participating in clinical trials of pharmaceuticals that were building scientific evidence of their efficacy and prior to requesting FDA approvals as to their suitability for sale to the public. As early as in the 1970s novel medical devices were developed in this country. Some of them such as the CO2 surgical laser and the CAT scanner were in the forefront of medical technology, In the 1990s Israel attracted global medical industry attention with the development of medical cardiac stents, the small coil like devices that are inserted into cardiac and other blood vessels, to prevent their collapse.

The management skills acquired in the early 1980s are now being put at the disposal of the startups of the current generation of medical and biotech companies.


Medical Devices Companies on the Move They attract 24% of all research and development grants from the Office of the Chief Scientist

86 high-tech companies raised at least $ 200 million in the last quarter of 2002

30% or $60 million of the total pie went into life science companies

The life sciences sector became prominent in the last quarter of the year


It is being suggested in the Israeli oriented venture capital community that that the medical devices field will not suffer a drop in demand similar to the one being experienced by the information technology and telecom industries worldwide. From a business point of view the aging populations in the developed world, government healthcare reforms and widespread evidence of improved fundamental and applied science all contribute to their belief that this is the area where money should be invested. Who are some of the companies that are obtaining investment support?

TopSpin Medical, (IHTIR 2/2003) a Lod, Israel-based company that is developing a platform for magnetic resonance imaging that does away with external magnets, and is working to miniaturize the technology for cardiac applications. TopSpin raised $16.5 million in a second round that was over-subscribed. The companys technology is appealing to investors but at least one cardiologist has told IHTIR that he is sceptical that the company can deliver on its promises.

Super Dimension Ltd., a Herzliya-based startup that is developing products for the diagnosis and treatment of lung disease. It recently obtained $13 million in a fourth round financing.

Iomai Corp., a developer of vaccine delivery systems to the skin also received funding whose sum was not disclosed.

Brainsgate Ltd., a maker of medical devices for drug delivery to the brain asl completed a financing round.

Percutaneous Valve Technologies Inc. announced the completion of a $14 million second round. The lead investors in the round included : Medtronic Inc., the worlds largest medical device company and Boston Scientific Corp. which has a long history of investment in Israels medical sector. Percutaneous Tech is developing an alternative product for heart valve replacement.

The BIRD Foundations choices for R & D grants also shows a growing bias in favor of life sciences.

Dov Hershberg, outgoing head of the BIRD Foundation was critical of the venture capital industry. He said that "many venture capital funds are floundering without direction. Ineffective decision processes, which led to the creation of the investment bubbles that collapsed over the past two years, are now resulting in an almost total lack of investment, with many missed opportunities. Global markets, which until recently were very promising, are now in a slump. The communications market, the semi-conductor industry, life sciences and other fields, have reached their lowest point in years. Therefore, this is an opportunity to invest. This is the time for experts and well informed investments with long-term strategy."

Of the total grants approved by BIRD, approximately $6 million, representing 42% of the total grants, is being invested in seven life sciences projects, with a combined budget of $16 million. From a total of 15 companies, BIRD-F approved a $1.0 million funding for C2Cure, formerly CByond, towards its R&D project titled Urological and Gynaecological Endoscope Development. IHTIR has published a CByond report in its October 2002 issue which also appears on the IHTIR web site http://ishitech.co.il/1002are3.htm.



Reprinted from the Israel High-Tech & Investment Report March 2003

Click HERE to request further information.
Click HERE to go BACK.