ISRAEL 
HIGH-TECH & INVESTMENT REPORT

from the March 2005 issue


Copaxone 2004 Sales Approach $1.0 billion

Teva Pharmaceuticals (TASE, Nasdaq:TEVA) announced that Copaxone sales, its medication for relapsing/remitting multiple sclerosis reached an all-time high of $936 million, up 30% from the year 2003. IMS Health, a source for pharmaceutical market intelligence and analysis, says Copaxone achieved a 32.6% share of the U.S. market in the second half of 2004, making it the biggest selling treatment in the States for MS.

Fourth-quarter Copaxone sales in the U.S. increased 23% versus the same period of 2003 to $175 million. U.S. sales for the year jumped 26% to $625 million. Year 2004 sales outside the U.S. leaped 38% to $311 million.

Copaxone, one of Teva's few proprietary drugs, is responsible for about 10% of Teva's turnover, and 15% of its net profit. Part of the pressure mounting on Teva stock in recent weeks has been due to perceived threats to Copaxone, mainly the upcoming launch of Tysabri, a medication from Biogen Iden (Nasdaq:BIIB) and Elan Pharmaceuticals.

Copaxone is administered by daily injection, but the patient can cope with it at home. Tysabri is convenient in requiring only a monthly injection, but it must be administered at a clinic.



Reprinted from the Israel High-Tech & Investment Report March 2005

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